Table V.
Overall survival and quality of life analysis.
| Variable | Total | PPPD | SPD | P-value |
|---|---|---|---|---|
| OS | 45.6 (4–144)c | 55.1 (4–142)c | 40.1 (4–144)c | 0.126a |
| OS of positive lymph nodes (EORTC)-QLQ-C30 | 25.2 (4–56)c | 27.4 (4–56)c | 24.0 (4–54)c | 0.592a |
| Physical functioning | ||||
| 6 months | 49.8 (18.2) | 53.6 (16.2) | 47.7 (19.1) | 0.189b |
| 24 months | 49.2 (15.4) | 52.3 (15.5) | 47.5 (15.3) | 0.210b |
| Role functioning | ||||
| 6 months | 50.9 (21.8) | 50.6 (23.8) | 51.1 (20.9) | 0.934b |
| 24 months | 41.8 (21.8) | 44.8 (24.8) | 40.2 (20.0) | 0.389b |
| Emotional functioning | ||||
| 6 months | 44.6 (14.6) | 40.9 (16.0) | 45.1 (14.0) | 0.742b |
| 24 months | 42.9 (17.5) | 43.3 (18.6) | 42.7 (17.1) | 0.893b |
| Cognitive functioning | ||||
| 6 months | 55.5 (22.3) | 57.0 (23.6) | 54.7 (21.8) | 0.673b |
| 24 months | 46.9 (20.8) | 48.7 (19.9) | 46.0 (21.4) | 0.600b |
| Social functioning | ||||
| 6 months | 39.1 (21.3) | 41.6 (23.2) | 37.6 (20.3) | 0.450b |
| 24 months | 47.4 (21.2) | 44.2 (23.5) | 49.2 (19.8) | 0.336b |
| Overall quality of life | ||||
| 6 months | 46.8 (16.1) | 43.9 (16.7) | 48.5 (15.7) | 0.244b |
| 24 months | 47.1 (20.0) | 49.3 (21.4) | 45.8 (19.3) | 0.477b |
| Appetite loss | ||||
| 6 months | 41.2 (31.4) | 26.9 (24.9) | 49.3 (32.0) | 0.003b,d |
| 24 months | 45.3 (28.6) | 47.3 (31.5) | 44.2 (27.2) | 0.649b |
| Nausea and vomiting | ||||
| 6 months | 41.0 (24.1) | 40.3 (25.0) | 41.3 (23.9) | 0.868b |
| 24 months | 38.1 (22.1) | 42.3 (24.1) | 35.8 (20.7) | 0.237b |
| Diarrhea | ||||
| 6 months | 29.1 (26.7) | 28.2 (26.1) | 29.7 (27.4) | 0.820b |
| 24 months | 22.6 (21.5) | 21.7 (20.9) | 23.1 (22.0) | 0.794b |
a
Log-rank test
b
Student's t-test.
c
Values are presented as the median (range), as opposed to the mean (standard deviation) presentation used for all other data.
d
P<0.05. PPPD, pylorus-preserving pancreaticoduodenectomy; SPD, standard pancreaticoduodenectomy; OS, overall survival; EORTC, European Organization for Research and Treatment of Cancer.