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. 2018 Mar 2;15(5):6265–6274. doi: 10.3892/ol.2018.8166

Figure 2.

Figure 2.

Antitumor effect of cell therapy. Following therapy, 8 mice in each group were monitored for 84 days. (A) In the early-effect study, the tumor volumes of mice in the hUMSC/IL-18 group were significantly decreased compared with the tumor volumes of mice in the PBS, hUMSC and hUMSC/vector groups from day 17 onwards. (B) In the late-effect study, the tumor volumes of mice in the hUMSC/IL-18 group were significantly decreased compared with the tumor volumes of mice in the PBS, hUMSC and hUMSC/vector groups from day 45 onwards. *P<0.05 vs. all other groups. hUMSCs, human mesenchymal stem cells derived from umbilical cord; IL-18, interleukin 18.