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Effect of MDR1 deficiency on female mouse ovarian function and fertility. The number of superovulated oocytes collected from oviduct (A) and the MII percentage of these oocytes (B) in WT and Mdr1a/b−/− female mice. C, The average number of litter size, gestation period, and sex ratio for 4 mating rounds in WT and Mdr1a/b−/− female mice. Error bar: SD (n = 4–6 female mice for each experiment and 3 replicates were performed).
