Table IV.
Association between SPARC gene expression and potential prognostic variables.
| SPARC expression | |||
|---|---|---|---|
| Variable | Low (n=73) | High (n=61) | P-value |
| Age, years | |||
| ≥65 | 43 | 35 | 0.499 |
| <64 | 30 | 26 | |
| Sex | |||
| Male | 48 | 44 | 0.273 |
| Female | 25 | 17 | |
| Histological type | |||
| Differentiated | 28 | 25 | 0.447 |
| Undifferentiated | 45 | 36 | |
| Tumor size | |||
| ≥60 mm | 44 | 30 | 0.133 |
| <60 mm | 29 | 31 | |
| Depth of invasion | |||
| T1-T3 | 29 | 24 | 0.553 |
| T4 | 44 | 37 | |
| Lymph node metastasis | |||
| Absent | 8 | 8 | 0.451 |
| Present | 65 | 53 | |
| Number of lymph node metastasis | |||
| 0–6 | 46 | 35 | 0.313 |
| ≥7 | 27 | 26 | |
| Lymphatic invasion | |||
| Absent | 17 | 13 | 0.475 |
| Present | 56 | 48 | |
| Venous invasion | |||
| Absent | 22 | 11 | 0.077 |
| Present | 51 | 50 | |
| TNM stage | |||
| II | 22 | 18 | 0.545 |
| III | 51 | 43 | |
SPARC, secreted protein, acidic and cysteine-rich; T, tumor stage; TNM, Tumor-Node-Metastasis.