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. 2018 Mar 21;15(5):4400–4408. doi: 10.3892/etm.2018.5980

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Copyright: © Wu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 6. — (A) Western blotting was performed to measure the activation of Cas3 and PARP. The expression of (B) Cas3, (C) activated Cas3, (D) PARP and (E) activated PARP was analyzed (F) Western blotting was performed to measure the expression of apoptosis-associated proteins. The expression of (G) Bax/Bcl-2 and (H) activated Cas9 was analyzed. *P<0.05. Cas, caspase; PARP, poly ADP-ribose polymerase; Bax, B-cell lymphoma 2-associated X protein; Bcl-2, B-cell lymphoma 2; NC, negative control; OD, oxygen deprivation; OSD, oxygen and serum deprivation; T, transforming growth factor-β3.