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. 2018 Mar 7;15(5):7007–7013. doi: 10.3892/ol.2018.8192

Table II.

Univariate and multivariate analysis of prognostic factors for disease-free survival in sporadic colorectal cancer.

95% CI for HR

Factors B SE Wald P-value HR Lower Upper
Univariate analysis
  Age (years) −0.358 0.194 3.398 0.065 0.699 0.478 1.023
  Sex 0.164 0.192 0.732 0.392 1.179 0.809 1.717
  Location −0.044 0.059 0.555 0.456 0.957 0.852 1.075
  Differentiation −0.862 0.188 21.044 0.001a 0.422 0.292 0.610
  Tumor stage 1.151 0.226 25.987 0.001a 3.162 2.031 4.923
  Lymph node status 1.239 0.123 101.937 0.001a 3.453 2.714 4.391
  Metastasis status 2.471 0.471 27.541 0.001a 11.834 4.703 29.779
  Invasion −1.033 0.194 28.264 0.001a 0.356 0.243 0.521
  MMR status 0.599 0.278 4.623 0.032a 1.819 1.054 3.140
Multivariate analysis
  Differentiation −0.574 0.208 7.623 0.006a 0.563 0.375 0.847
  Tumor stage 1.283 0.232 30.586 0.001a 3.606 2.289 5.680
  Lymph node status 1.333 0.149 79.598 0.001a 3.793 2.830 5.083
  Metastasis status 0.593 0.503 1.391 0.238 1.809 0.676 4.845
  Invasion 0.324 0.112 1.892 0.329 0.672 0.492 1.168
  MMR status 0.863 0.288 8.985 0.003a 2.369 1.348 4.165
a

P<0.05. B, partial regression coefficient; SE, standard error of partial regression coefficient; CI, confidence interval; HR, hazard ratio; MMR, DNA mismatch repair. Wald was used to compare if there was difference between total partial regression coefficient and 0.