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. 2018 Mar 19;15(5):7649–7654. doi: 10.3892/ol.2018.8294

Figure 3.

Figure 3.

miR-874 regulates osteosarcoma cell proliferation by repressing CDK9 expression. (A) pcDNA-CDK9 rescued the regulation of miR-874 on CDK9 expression. *P<0.01 vs. control group; **P<0.01 vs. miR-874 mimics group. (B) MTT assay was utilized to analyze the effect of miR-874 on cell proliferation of MG-63 cells. The groups were as follows: miR-874 mimics (MG-63 cells transfected with miR-874 mimics); pcDNA-CDK9 (MG-63 cells transfected with pcDNA-CDK9); and miR-874 mimics+CDK9 (MG-63 cells co-transfected with miR-874 mimics and pcDNA-CDK9). Data are presented as the mean ± standard deviation from three independent experiments. *P<0.01 vs. control group; **P<0.01 vs. miR-874 mimics group. CDK9, cyclin-dependent kinase 9; miR-874, microRNA-874.