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. 2018 Mar 16;8(5):466–474. doi: 10.3892/br.2018.1079

Table II.

Body weight, food intake and lipid metabolic parameters in rats fed an HSR or HSC diet with or without PA (experiment 1).

HSR HSR + PA HSC HSC + PA




Variables Mean SEM Mean SEM Mean SEM Mean SEM
Final body weight, g 171 4 176 4 178 1 183 2
Food intake, g/12 day 174a 4 177a,b 4 188b,c 2 193b 3
Liver
  Weight, g/100 g body wt. 4.64a 0.10 4.71a 0.12 5.84b 0.13 5.70b 0.06
  Total lipids, mg/g liver 64.2a 3.6 57.8a 1.2 106.2b 6.2 62.5a 1.4
  Triglyceride, mg/g liver 17.5b 1.9 12.0a 0.3 51.6c 5.6 23.2b 1.6
  Cholesterol, mg/g liver 3.22 0.29 3.13 0.15 3.56 0.15 3.04 0.13
  G6PD activity, mU/mg protein 34.1a 5.4 36.7a 1.7 69.1b 7.8 53.1a,b 6.6
  ME activity, mU/mg protein 28.9a 2.9 32.1a 2.8 50.6b 5.6 35.7a,b 3.5
    G6PD expression 1.00a 0.12 0.89a 0.10 1.71b 0.09 1.12a 0.09
  ME1 expression 1.00a,b 0.06 0.72a 0.05 2.08c 0.07 1.09b 0.06
  FAS expression 1.00a 0.11 0.88a 0.16 2.79b 0.78 2.21a,b 0.06

Mean values with their SEM; n=6.

a-c

Mean values with unlike superscript letters were significantly different, P<0.05 (Tukey post hoc test for body weight, food intake, liver weight, hepatic cholesterol, hepatic ME activity, hepatic gene expression of lipogenic enzymes; Steel-Dwass test for liver total lipids, hepatic triglyceride and hepatic G6PD activity). HSR, high-starch; HSC, high-sucrose; PA, sodium phytate; G6PD, glucose-6-phosphate dehydrogenase; ME, malic enzyme; FAS, fatty acid synthetase; SEM, standard error of the mean.