Table 2.
Univariate and multivariate analysis of demographic and imaging covariates for immediate objective response (OR). On multivariate analysis, apparent diffusion coefficient (ADC) was the only covariate identified that correlated with OR.
| Univariate P | Odds Ratio | Multivariate P | |
|---|---|---|---|
| Age | 0.59 | - | - |
| Gender | 0.08 | 2.7 (0.65–11.5) | 0.16 |
| Index lesion size | 0.86 | - | - |
| Childs-Pugh score | 0.61 | - | - |
| Tumor multifocality | 0.33 | - | - |
| Presence of vascular invasion | 0.53 | - | - |
| ADC ≥ 1.01 × 10−3 mm2/s | 0.03 | 4.4 (1.2–18.6) | 0.03 |
| ECOG status | 0.79 | - | - |
| Pre-procedure total bilirubin | 0.30 | - | - |
| BCLC classification | 0.20 | - | - |
| Treatment modality | 0.15 | ||
| Doxorubicin dose | 0.44 | - | - |
| Yttrium-90 absorbed dose | 0.11 | − | − |
ADC-apparent diffusion coefficient, ECOG-extra-hepatic metastases, BCLC-Barcelona Clinic Liver Cancer.