Table 2.
Summary of photon budget parameters for different source depths in tissue, using optimal wavelength range.
| Imaging Type | Cherenkov | CEL: PtG4 | CEL: Ir | |||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Pulses | 30 | |||||||||||||||||
| Dose (cGy) | 0.83 | |||||||||||||||||
| Gate Width (us) | 4 | 300 | 55 | |||||||||||||||
| Wavelength (nm) | 700–800 | 700–800 | 600–700 | |||||||||||||||
| Depth | 1 | 2 | 3 | 5 | 10 | 15 | 1 | 2 | 3 | 5 | 10 | 15 | 1 | 2 | 3 | 5 | 10 | 15 |
| Source | 9.76E+06 | 9.76E+06 | 1.21E+07 | |||||||||||||||
| Tissue output | 6.78E+06 | 4.71E+06 | 3.28E+06 | 1.59E+06 | 2.67E+05 | 4.58E+04 | 3.98E+05 | 2.80E+05 | 1.97E+05 | 9.75E+04 | 1.71E+04 | 3.07E+03 | 1.40E+05 | 7.68E+04 | 4.28E+04 | 1.39E+04 | 9.89E+02 | 8.25E+01 |
| Lens output (f/1.2 0.63m) | 4.67E+00 | 3.25E+00 | 2.26E+00 | 1.10E+00 | 1.84E−01 | 3.16E−02 | 2.74E−01 | 1.93E−01 | 1.36E−01 | 6.72E−02 | 1.18E−02 | 2.12E−03 | 9.68E−02 | 5.29E−02 | 2.95E−02 | 9.57E−03 | 6.82E−04 | 5.69E−05 |
| Photocathode output | 1.31E+00 | 9.07E−01 | 6.31E−01 | 3.06E−01 | 5.09E−02 | 8.69E−03 | 1.15E−02 | 8.09E−03 | 5.69E−03 | 2.82E−03 | 4.93E−04 | 8.82E−05 | 4.54E−03 | 2.48E−03 | 1.38E−03 | 4.48E−04 | 3.19E−05 | 2.66E−06 |
| MCP output (Single stage) | 1.31E+04 | 9.07E+03 | 6.31E+03 | 3.06E+03 | 5.09E+02 | 8.69E+01 | 1.15E+02 | 8.09E+01 | 5.69E+01 | 2.82E+01 | 4.93E+00 | 8.82E−01 | 4.54E+01 | 2.48E+01 | 1.38E+01 | 4.48E+00 | 3.19E−01 | 2.66E−02 |
| Phosphor screen output (P43) | 2.61E+06 | 1.81E+06 | 1.26E+06 | 6.12E+05 | 1.02E+05 | 1.74E+04 | 2.30E+04 | 1.62E+04 | 1.14E+04 | 5.63E+03 | 9.86E+02 | I.76E+02 | 9.08E+03 | 4.96E+03 | 2.77E+03 | 8.97E+02 | 6.38E+01 | 5.32E+00 |
| CCD detection | 4.96E+05 | 3.45E+05 | 2.40E+05 | 1.16E+05 | 1.93E+04 | 3.30E+03 | 4.38E+03 | 3.07E+03 | 2.16E−03 | 1.07E+03 | 1.87E+02 | 3.35E+01 | 1.72E+03 | 9.43E+02 | 5.25E+02 | 1.70E+02 | 1.21E+01 | 1.01E+00 |
| Photocathode EBI | 9.60E−06 | 7.20E−04 | 1.32E−04 | |||||||||||||||
| MCP EBI | 9.60E−02 | 7.20E+00 | 1.32E+00 | |||||||||||||||
| Phosphor screen EBI | 1.92E+01 | 1.44E+03 | 2.64E+02 | |||||||||||||||
| CCD noise | 5.41E+02 | 3.49E+01 | 2.05E+01 | |||||||||||||||
| Total noise | 5.41E+02 | 1.44E+03 | 2.65E+02 | |||||||||||||||
| Approximate Pixel Intensity | 62518 | 43438 | 30207 | 14648 | 2439 | 416 | 552 | 387 | 272 | 135 | 24 | 4 | 217 | 119 | 66 | 21 | 2 | 0 |
| Approximate Noise Intensity | 68 | 182 | 33 | |||||||||||||||
| Signal to Background Ratio | 917.1 | 637.2 | 443.1 | 214.9 | 35.8 | 6.1 | 3.0 | 2.1 | 1.5 | 0.7 | 0.1 | 0.0 | 6.5 | 3.6 | 2.0 | 0.6 | 0.0 | 0.0 |