Table II.
Cox-regression analysis of various prognostic parameters in patients for all patients.
| Univariate | Multivariate | |||
|---|---|---|---|---|
| Factor | HR (95% CI) | P-value | HR (95% CI) | P-value |
| Sex | ||||
| Male | Reference | |||
| Female | 0.592 (0.261–1.344) | 0.210 | – | – |
| Age, years | ||||
| ≥60 | Reference | |||
| <60 | 0.835 (0.549–1.270) | 0.399 | – | – |
| Lymphatic metastasis | ||||
| Positive | Reference | |||
| Negative | 0.565 (0.197–1.619) | 0.288 | – | – |
| Tumor size, cm | ||||
| ≥5 | Reference | |||
| <5 | 4.514 (1.515–13.453) | 0.007 | – | – |
| Histological grade | ||||
| 1 | Reference | |||
| 2 | 0.879 (0.355–2.175) | 0.781 | – | – |
| 3 | 1.167 (0.404–3.370) | 0.775 | – | – |
| Clinical stage | ||||
| I–II | Reference | |||
| III | 2.698 (0.925–7.866) | 0.069 | – | – |
| IV | 2.832 (0.729–11.001) | 0.133 | – | – |
| Pathological type | ||||
| Adenocarcinoma | Reference | |||
| Others | 1.034 (0.350–3.048) | 0.952 | – | – |
| TARBP1 | ||||
| Positive | Reference | Reference | ||
| Negative | 0.133 (0.036–0.484) | 0.002 | 2.729 (1.471–5.061) | 0.003 |
TARBP, transactivation response RNA-binding protein; HR, hazard ratio; CI, confidence interval.