Figure 1. Renin-independent aldosteronism and the incidence rate of hypertension.
Figures depict the unadjusted incidence rate of hypertension (number of incident cases per 1,000 person-years at risk) by phenotypes of renin and quartiles of aldosterone. Conversion of plasma renin activity (PRA) from SI to conventional units: 1 μg/L/h = 1 ng/mL/h. Conversion of aldosterone from SI to conventional units: 1 pmol/L=0.036 ng/dL. Quartiles of aldosterone in conventional units are: Q1 (<9.23 ng/dL), Q2 (9.23–12.73 ng/dL), Q3 (12.74–17.32 ng/dL), Q4 (≥17.32 ng/dL). A) Participants with a suppressed renin phenotype (PRA ≤ 0.50 μg/L/h); B) Participants with an indeterminate renin phenotype (PRA 0.51–0.99 μg/L/h); C) Participants with an unsuppressed renin phenotype (PRA ≥ 1.0 μg/L/h).