Increasing HbA1c is associated with increased risk of short-term myocardial infarction (MI), specifically among individuals with obstructive CAD. (A) Unadjusted and adjusted associations between HbA1c categories and MI in the entire study population. (B) Adjusted associations between HbA1c categories and MI in participants with no CAD, non-obstructive CAD, and obstructive CAD. The pattern of association between HbA1c and MI varied significantly across categories of CAD severity (p-value for interaction < 0.0001). There were too few MI events to accurately model the association in several HbA1c categories among those with non-obstructive (64 ≤ HbA1c < 75 mmol/mol) and no CAD (HbA1c < 42 mmol/mol, 64 ≤ HbA1c < 75 mmol/mol, and HbA1c ≥ 75 mmol/mol).