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. Author manuscript; available in PMC: 2019 Apr 21.
Published in final edited form as: Lancet. 2018 Feb 7;391(10130):1599–1607. doi: 10.1016/S0140-6736(18)30204-6

Table 3.

Prevalence of latent yaws in subgroups determined by age

Time
(month)
Children aged 1 – 5 years Children aged 6 – 15 years
No. of
children
tested
All Cases of Latent Yaws* High-titre Latent Yaws No. of
children
tested
All Cases of Latent Yaws* High-titre Latent Yaws
no. of
children
(%)
Adjusted
prevalence ratio
(95%CI)§
no. of
children
(%)
Adjusted
prevalence ratio
(95%CI)
no. of
children
(%)
Adjusted
prevalence ratio
(95%CI) ∥∥∥
no. of
children
(%)
Adjusted
prevalence ratio
(95%CI)**
Baseline 117 26 (22·2) 1 16 (13·7) 1 874 299 (34·2) 1 165 (18·9) 1
6 mo 77 10 (13·0) 0·58 (0·20; 1·74) 6 (7·8) 0·57 (0·15; 2·19) 797 251 (31·5) 0·92 (0·55; 1·53) 117 (14·7) 0·78 (0·40; 1·53)
12 mo 114 6 (5·3) 0·24 (0·09; 0·63) 1 (0·9) 0·06 (0·01; 0·48) 796 143 (18·0) 0·53 (0·35; 0·79) 58 (7·3) 0·39 (0·19; 0·77)
18 mo 81 9 (11·1) 0·50 (0·22; 1·12) 1 (1·2) 0·09 (0·02; 0·52) 462 129 (27·9) 0·82 (0·55; 1·22) 50 (10·8) 0·57 (0·34; 0·98)
24 mo 69 6 (8·7) 0·39 (0·17; 0·88) 1 (1·4) 0·11 (0·01; 0·75) 445 113 (25·4) 0·74 (0·48; 1·15) 24 (5·4) 0·29 (0·16; 0·52)
30 mo 65 4 (6·2) 0·28 (0·10; 0·79) 0 (0·0) -- 416 136 (32·7) 0·96 (0·62; 1·48) 33 (7·9) 0·42 (0·18; 0·97)
36 mo 66 3 (4·5) 0·20 (0·05; 0·80) 1 (1·5) 0·11 (0·02; 0·78) 470 130 (27·7) 0·81 (0·47; 1·40) 22 (4·7) 0·25 (0·08; 0·81)
42mo. 68 6 (8·8) 0·40 (0·17; 0·94) 0 (0·0) -- 422 84 (19·9) 0·58 (0·37; 0·91) 28 (6·6) 0·35 (0·20; 0·62)
*

The analysis included all seropositive children with a reactive TPHA and RPR titre of at least 1:2.

The analysis included children with a reactive TPHA and RPR titre of at least 1:16.

The adjusted prevalence ratio was calculated with the use of the cluster option of a log-binomial regression model. The baseline prevalence is the reference value.

§

P = 0·0165 for the significance of the model overall.

P = 0·0014 for the significance of the model overall

P = 0·0024 for the significance of the model overall

**

P = 0·0002 for the significance of the model overall.

Baseline, 6 and 12 month data were previously published (Ref. 7) and are included here for comparison to later time points