Extended data Table 1.
Aetiology of skin ulcers prior to MDA of azithromycin and in subsequent rounds of targeted treatment *†
| Time (month) | Participants tested for PCR |
Treponema pallidum subsp. pertenue only detected |
Both T. p. pertenue and H. ducreyi detected |
Haemophilus ducreyi only detected |
Negative for T. pallidum and H. ducreyi |
|---|---|---|---|---|---|
| no. | no. of participants (%) | ||||
| Baseline | 90* | 19 (21·1) | 12 (13·3) | 42 (46·7) | 17 (18·9) |
| 6 mo. | 84* | 14 (16·7) | 27 (32·1) | 32 (38·1) | 11 (13·1) |
| 12 mo. | 114 | 12 (10·5) | 7 (6·1) | 53 (46·5) | 42 (36·8) |
| 18 mo. | 88 | 12 (13·6) | 5 (5·7) | 35 (39·8) | 36 (40·9) |
| 24 mo. | 68 | 6 (8·8) | 7 (10·3) | 28 (41·2) | 27 (39·7) |
| 30 mo. | 120 | 19 (15·8) | 12 (10·0) | 63 (52·5) | 26 (21·7) |
| 36 mo. | 107 | 24 (22·4) | 12 (11·2) | 49 (45·8) | 22 (20·6) |
| 42mo. | 107 | 37 (34·6) | 14 (13·1) | 30 (28·0) | 26 (24·3) |
*
Data of PCR-confirmed yaws cases for baseline and 6 months represent a random sample of 90 and 84 ulcers that were tested by PCR from a total of 690 and 121 participants with skin ulcers detected, respectively. Data from 12 months to 42 months represent all ulcers detected.
†
P<0.0001 by the chi-square test for the between-group comparison within each type of infection.