Table 1.
Top ten up- and down- regulated genes in ovarian cancer cells co-cultured with adipocytes
| Number | Symbol | Entrez Gene Name | P-value | False Discovery Rate (q-value) |
|---|---|---|---|---|
| UPREGULATED | ||||
| 1 | IL8 | interleukin 8 | 3.08E-04 | 1.60E-02 |
| 2 | IFITM1 | interferon induced transmembrane protein 1 | 5.10E-06 | 5.68E-03 |
| 3 | ISG15 | ISG15 ubiquitin-like modifier | 3.95E-04 | 1.60E-02 |
| 4 | IFI27 | interferon, alpha-inducible protein 27 | 1.79E-04 | 1.60E-02 |
| 5 | MX1 | myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) | 7.29E-04 | 1.60E-02 |
| 6 | IFI6 | interferon, alpha-inducible protein 6 | 6.96E-04 | 1.60E-02 |
| 7 | OAS3 | 2′-5′-oligoadenylate synthetase 3, 100kDa | 2.24E-04 | 1.60E-02 |
| 8 | IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 6.46E-04 | 1.60E-02 |
| 9 | SOD2 | superoxide dismutase 2, mitochondrial | 4.52E-04 | 1.60E-02 |
| 10 | IRF9 | interferon regulatory factor 9 | 6.38E-06 | 5.68E-03 |
| DOWNREGULATED | ||||
| 1 | GPR56 | G protein-coupled receptor 56 | 9.28E-04 | 1.66E-02 |
| 2 | ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | 3.88E-04 | 1.60E-02 |
| 3 | EGR1 | early growth response 1 | 1.15E-02 | 3.05E-02 |
| 4 | TM7SF2 | transmembrane 7 superfamily member 2 | 7.30E-05 | 1.42E-02 |
| 5 | MMP7 | matrix metallopeptidase 7 (matrilysin, uterine) | 5.17E-04 | 1.60E-02 |
| 6 | ACSS2 | acyl-CoA synthetase short-chain family member 2 | 9.90E-04 | 1.70E-02 |
| 7 | CLIC3 | chloride intracellular channel 3 | 3.33E-03 | 2.18E-02 |
| 8 | HES2 | hairy and enhancer of split 2 (Drosophila) | 2.85E-03 | 2.10E-02 |
| 9 | UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) | 1.00E-03 | 1.71E-02 |
| 10 | CGNL1 | cingulin-like 1 | 9.18E-04 | 1.66E-02 |