Table 2.
Ingenuity Pathway Analysis predicted top five diseases/functions categories increased or decreased in ovarian cancer cells co-cultured with adipocytes
| Number | Diseases or Functions Annotation | P-value | Z-score |
|---|---|---|---|
| UPREGULATED | |||
| 1 | Cell survival | 5.05E-09 | 3.540 |
| 2 | Cell viability | 1.49E-07 | 3.467 |
| 3 | Proliferation of cells | 2.52E-19 | 3.260 |
| 4 | Cytokinesis of tumor cell lines | 1.69E-12 | 2.889 |
| 5 | Metastasis of tumor | 3.08E-05 | 2.859 |
| DOWNREGULATED | |||
| 1 | Infection of mammalia | 8.83E-05 | −3.901 |
| 2 | Organismal death | 2.57E-09 | −3.820 |
| 3 | Replication of VSV | 6.92E-05 | −2.750 |
| 4 | Synthesis of lipid | 3.84E-05 | −2.403 |
| 5 | Morphology of lymphatic system component | 1.79E-04 | −2.378 |