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. Author manuscript; available in PMC: 2018 Aug 2.
Published in final edited form as: Lab Invest. 2018 Feb 2;98(4):477–488. doi: 10.1038/s41374-017-0016-1

Figure 5. EPEC suppresses apoptosis associated with DSS-induced colitis.

Figure 5

Mice were treated with DSS then infected with various EPEC strains as described in figure 4A plus an additional group infected with ΔH1/H2 complemented with inducible plasmid harboring nleH1-K159A (Δ+H1-K159A). Distal colonic tissues were immunostained (a) and quantitated (b) at 9dpt for cleaved caspase-3. Representative image and analysis of n>20 high-powered fields from n=4 mice. Statistical analysis was by ANOVA using Tukey post-hoc tests (*, p<0.05; ***, p<0.001; vs. DSS alone). Scale bars: 25 µm.