Table V.
Studies evaluating the prognostic values of miRNAs using survival analysis.
| Name | P-value | HR (95% CI) | Method | Refs. |
|---|---|---|---|---|
| RFS | ||||
| miR-20a | 0.0100 | ND | K-M | (93) |
| miR-148a | 0.0200 | ND | K-M | (93) |
| PFS | ||||
| miR-25 | 0.0340 | 0.920 (0.840, 0.990) | Univariate Cox regression | (94) |
| miR-483 | 0.0250 | ND | K-M | (87) |
| miR-33b | 0.0160 | ND | Univariate Cox regression | (15) |
| miR-19 | 0.0030 | 2.787 (1.421, 5.468) | Multivariable Cox regression | (43) |
| miR-15a | 0.0080 | 0.260 (0.090, 0.710) | Multivariable Cox regression | (88) |
| miR-214 | 0.0150 | ND | K-M | (35) |
| OS | ||||
| miR-25 | 0.0005 | 0.810 (0.720, 0.910) | Univariate Cox regression | (94) |
| miR-25 | 0.0130 | 0.760 (0.620, 0.940) | Multivariable Cox regression | (94) |
| miR-744 | 0.0001 | 0.670 (0.548, 0.819) | Univariate Cox regression | (14) |
| Let-7e | 0.0020 | 0.611 (0.450, 0.829) | Univariate Cox regression | (14) |
| miR-33b | 0.0330 | ND | Univariate Cox regression | (15) |
| miR-19 | 0.0230 | 2.995 (1.167, 7.690) | Multivariable Cox regression | (43) |
| miR-15a | 0.0350 | 0.280 (0.080, 0.930) | Multivariable Cox regression | (88) |
| miR-214 | 0.0020 | ND | K-M | (35) |
miRNA/miR, microRNA; HR, hazard ratio; CI, confidence interval; ND, not determined; RFS, relapse-free survival; PFS, progression-free survival; OS, overall survival; K-M, Kaplan-Meier method; multivariable Cox regression, multivariable Cox proportional hazards regression model, univariate Cox regression, univariate Cox proportional hazards regression model; Refs., references.