Table 2.

Descriptive statistics for included NIH grants on implementation science in genomic medicine (funding initiated 2012–2017).

Study Design Characteristics			Genomic Research Foci			Implementation Science Foci
	n	%		n	%		n	%
Translational Research Phase			Type of genetic test			Implementation Science
T2	5	11.9	Germline	31	73.8	Implementation	37	88.1
T3	36	81.0	Somatic	4	9.5	Dissemination	12	28.6
T4	1	2.4	NA	4	9.5	Adoption	2	4.8
			Cell-free DNA	3	7.1
Methods			Type of genetic test			Sustainability
Qualitative	35	83.3	NA/NR	16	38.1	Cost analysis	5	11.9
Quantitative	32	76.2	Single Gene	9	21.4	Capacity building	3	7.1
Cost	4	9.5	WGS	6	14.3	Maintenance	1	2.4
Other	3	7.1	Gene Panel	5	11.9
Comparative	3	7.1	WES	5	11.9
Simulation	1	2.4	Other	2	4.8
			Unknown	1	2.4
Study Design			Purpose of Genetic Test			IS Framework/Conceptual Model
Cross sectional	25	59.5	Oncology	19	45.2	For formative research (e.g. exploratory, qualitative research)	2	4.8
Cohort	9	21.4	Other	12	28.6	For intervention design	1	2.4
Randomized	9	21.4	Newborn Screening	3	7.1	Measured variables (e.g. primary or secondary outcomes)	1	2.4
Pre/Post	7	16.7	Prenatal	3	7.1
Other	3	7.1	General Clinical Seq.	2	4.8
Simulation	2	4.8	NA	2	4.8
Case Control	1	2.4
Unit of analysis						Collaborative Processes
Individual	35	83.3				None	27	64.3
Study Site	3	7.1				Patient engagement	5	11.9
Unclear	3	7.1				Stakeholder	5	11.9
						Designing for dissemination	2	4.8
						Team Science	2	4.8
						CBPR	1	2.4
Research Setting						IS Outcomes
Clinical	32	76.1				Patient-centeredness	22	52.4
Other	5	11.9				Uptake	14	33.3
Public Health	4	9.5				Feasibility	11	26.2
Both	1	2.4				Effectiveness	10	23.8
						Acceptability	6	14.3
						Costs	5	11.9
						Satisfaction	5	11.9
						Fidelity	3	7.1
						Equity	3	7.1
						Efficiency	2	4.8
						More than 3	2	4.8
						Other	1	2.4

Proportions are not mutually exclusive.