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. Author manuscript; available in PMC: 2018 Oct 2.
Published in final edited form as: Urol Oncol. 2017 May 8;36(10):459–468. doi: 10.1016/j.urolonc.2017.04.007

Fig. 3.

Fig. 3

Phylogenetic tree of the human B7 and CD28 families. Group I (green) includes B7-1/B7-2/CD28/CTLA-4, and B7h/ICOS/CD28/CTLA-4. Group II (blue) consists of PD-L1/PD-L2/PD-1, PD-L1/B7-1, and PD-L2/RGMb. Group III (red) contains B7-H3, B7x, and HHLA2/TMIGD2. (Color version of the figure available online.)