Skip to main content
. Author manuscript; available in PMC: 2020 May 1.
Published in final edited form as: Physiol Behav. 2017 Oct 26;203:70–80. doi: 10.1016/j.physbeh.2017.10.025

Fig. 5.

Fig. 5

Effects of acute gonadal hormone manipulations on ethanol self-administration. Though significant increases in active lever presses during reinstatement (REIN) relative to extinction (EXT) were evident in all groups, no significant effects of either prior chronic nor acute manipulation of estradiol in females (A) or testosterone in males (B) were evident. Significant and sex differences were evident for responding on the day of reinstatement. Sample sizes are shown within the bars of each graph. #p<0.001 (day effect); *p<0.001 (sex effect on reinstatement day only)