Figure 6.

C3 exoenzyme incubation decreased Runx2, Rho and ROCK protein expression in human dental pulp stem cells. Regulation of Runx2, RhoA and ROCK protein expression by the Rho/ROCK signaling pathway in human dental pulp stem cells (A) without and (B) with mineralization treatment. The inhibitor was C3 exoenzyme. Cells that received mineralization treatment were incubated for 0 (control), 7 or 21 days. Data are presented as the mean ± standard error of the mean of at least three experiments. **P<0.01 vs. Control. Runx2, runt-related transcription factor 2; ROCK, Rho-associated protein kinase.