Figure 1.

Resveratrol structure and resveratrol, rapamycin and combination treatment suppresses cell viability of MM cells. (A) Molecular structure of resveratrol. (B) Inhibitory effect of resveratrol on the viability of human MM cells. (C) Inhibitory effect of rapamycin on the viability of human MM cells. (D) Effect of resveratrol, rapamycin and their combination on MM cell viability. Cells were treated with dimethyl sulfoxide as a vehicle control or with resveratrol (60 µM), rapamycin (20 nM) or their combination [resveratrol (60 µM) + rapamycin (20 nM)] for 24 h and cell viability was determined using an MTT assay. *P<0.05, **P<0.01 vs. vehicle control. MM, multiple myeloma; Res, resveratrol; Rap, rapamycin.