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. 2018 Mar 12;15(5):7328–7334. doi: 10.3892/ol.2018.8240

Figure 1.

Figure 1.

miR-149 expression is downregulated in ovarian cancer tissues and cell lines. The miR-149 expression levels in (A) ovarian cancer tissues and corresponding normal tissues, as well as in (B) sensitive and insensitive ovarian cancer tissues to chemotherapy, were measured by RT-qPCR. (C) Correlation between the expression level of miR-149 and patient prognosis was analyzed by Kaplan-Meier survival analysis. (D) miR-149 expression levels in four ovarian cancer cell lines (HG-SOC, HO8910, SKOV-3 and ES2) and one immortalized normal fallopian tube epithelial cell line (FTE187) were measured by RT-qPCR. Error bars represent the mean ± standard deviation of at least three independent experiments. **P<0.01 vs. control group. XIAP, X-linked inhibitor of apoptosis; miR, microRNA; RT-qPCR, reverse transcription-quantitative polymerase chain reaction.