Skip to main content
. Author manuscript; available in PMC: 2018 Apr 27.
Published in final edited form as: Chemistry. 2015 Aug 18;21(39):13598–13608. doi: 10.1002/chem.201502211

Figure 10. The structural changes induced on Hsp90 by 18 compared to the symmetric 2CG9 structure.

Figure 10

The superposition exemplifies the distortion induced by the small molecules in protomer B (in red) compared to the original X-ray structure (pdb 2CG9, in blue). Protomer A from both structures are highly superimposable and are shown in light gray for simplicity.