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. Author manuscript; available in PMC: 2018 Apr 27.
Published in final edited form as: Chemistry. 2015 Aug 18;21(39):13598–13608. doi: 10.1002/chem.201502211

Figure 9. Inhibition of Hsp90 chaperone function.

Figure 9

Loss of Hsp90 client proteins in human cancer cells treated for 72 h with compounds 1, 4, 10, 12, 18, 19 or 17-AAG (IC50) and analyzed by Western blotting. β-actin was used to confirm equal protein loading on the gel.