Table I.
Associations between WDR5 tumor expression and clinicopathological parameters.
| WDR5 expression | ||||
|---|---|---|---|---|
| Variable | Cases, n | High | Low | P-value |
| Sex | NS | |||
| Male | 62 | 40 | 22 | |
| Female | 51 | 39 | 12 | |
| Age (years) | NS | |||
| ≥50 | 65 | 44 | 21 | |
| <50 | 48 | 35 | 13 | |
| AFP (ng/ml) | NS | |||
| >400 | 52 | 38 | 14 | |
| ≤400 | 61 | 41 | 20 | |
| HBsAg | NS | |||
| Negative | 54 | 37 | 17 | |
| Positive | 59 | 42 | 17 | |
| Liver cirrhosis | NS | |||
| No | 45 | 34 | 11 | |
| Yes | 68 | 45 | 23 | |
| Histological grade | 0.038 | |||
| Well/moderate | 53 | 32 | 21 | |
| Poor | 60 | 47 | 13 | |
| Tumor size | 0.023 | |||
| ≥5 | 58 | 35 | 23 | |
| <5 | 55 | 44 | 11 | |
| TNM stage | 0.035 | |||
| I–II | 56 | 34 | 22 | |
| III–IV | 57 | 45 | 12 | |
WDR5, WD repeat domain 5; NS, not significant; AFP, α-fetoprotein; HBsAg, hepatitis B surface antigen; TNM, tumor-node-metastasis.