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. 2018 Mar 22;15(5):8079–8087. doi: 10.3892/ol.2018.8323

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Figure 2. — Cellular internalization and cytotoxicity of NPs. (A) Transmission electron microscope image of the oxaliplatin-Au-Fe₃O₄-Herceptin NPs in SGC-7901 cells via endocytosis (arrow) following 2 h incubation. (B) The viability of SGC-7901 cells was not significantly affected until treated with Au-Fe₃O₄ with a Fe concentration >100 µg/ml. (C) The viability of SGC-7901 cells was significantly decreased following incubation with oxaliplatin-Au-Fe₃O₄-Herceptin, compared with control. *P<0.01 vs. 0 µg/ml Fe. NPs, nanoparticles.