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. 2018 Apr 25;18:195. doi: 10.1186/s12879-018-3104-y

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — Survival curves of vaccinated BALB/c mice after lethal challenge with two clinical S. aureus strains. Mice immunized with N106, N19 and N20 were challenged with S. aureus USA 300 (a) or Newman strains (b, c)(5E + 07 CFU) by intravenous injection (n = 8–9/group). Mice were monitored for 14 days. Log rank (Mantel-Cox) tests were conducted to compare the protection induced by different vaccination. Results from one of two representative experiments are shown