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. 2018 Apr 27;37:91. doi: 10.1186/s13046-018-0760-0

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — The expression of TRAF6 was elevated in OSCC patients. a The protein level of TRAF6 in OSCC samples and paired normal tissues was analyzed by Western blot. b The protein level of TRAF6 in human OSCC samples and paired normal tissues was analyzed by IHC. Cancer-specific survival by the Kaplan-Meier method by (c) the expression of TRAF6 in all patients (p = 0.280), (d) the expression of TRAF6 in patients with well differentiated tumors (N = 60; p = 0.074), (e) AJCC N stage (N0–1 vs. N2–3) (p = 0.034), and (f) Risk groups stratified by differentiation and expression of TRAF6 (p = 0.033)