Fig. 1.

A diagram of the protocol. WT, wild-type mice; EPHX2−/−, soluble epoxide hydrolase (sEH) gene knockout mice; D/W ratio, lung dry/wet weight ratio; EETs, epoxyeicosatrienoic acids; TNF-α, tumor necrosis factor-α; MIP-2, macrophage inflammatory protein-2; BALF, bronchoalveolar lavage fluid; Nrf2, nuclear-factor erythroid 2-related factor 2; Keap1, Kelch-like ECH-associated protein 1; HO-1, heme oxygenase-1; SOD, superoxide dismutase; ROS, reactive oxygen species