TABLE 2.
Progression-Free Survival | ||||
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Variables | HR | 95% CI | P | Reference |
Pretreatment CA125 level continuous | 1.00 | 1.00–1.00 | 0.128 | Continuous |
Posttreatment CA125 level continuous | 1.00 | 1.00–1.00 | 0.009 | Continuous |
Posttreatment CA125 level | ||||
Positive | 2.69 | 1.82–3.99 | <0.001 | Negative |
Unknown | 1.23 | 0.86–1.75 | 0.251 | |
Age | 1.01 | 0.99–1.02 | 0.243 | Continuous |
Ethnic Group – not white | 0.87 | 0.62–1.23 | 0.436 | White |
Disease site | 0.93 | 0.68–1.28 | 0.667 | Ovary |
Histology group | ||||
Papillary serous | 0.75 | 0.51–1.10 | 0.14 | Serous |
Mixed | 0.75 | 0.53–1.06 | 0.102 | |
Other | 0.59 | 0.38–0.92 | 0.019 | |
FIGO stage | ||||
III | 2.21 | 1.12–4.35 | 0.022 | ≤II |
IV | 4.83 | 2.41–9.68 | <0.001 | |
Unknown | 2.72 | 1.05–7.06 | 0.04 | |
Residual disease | ||||
<2 cm | 1.60 | 1.14–2.25 | 0.006 | No residual |
>2 cm | 2.64 | 1.79–3.9 | <0.001 | |
Unknown | 1.89 | 1.14–3.13 | 0.013 | |
Optimal debulking (operation note) | ||||
Yes | 0.57 | 0.41–0.78 | <0.001 | No |
Unknown | 0.60 | 0.24–1.5 | 0.272 | |
Neoadjuvant chemotherapy | ||||
No | 0.56 | 0.43–0.74 | <0.001 | Yes |
Unknown | 1.02 | 0.32–3.24 | 0.968 | |
Status postchemotherapy | ||||
Disease present | 2.42 | 1.79–3.26 | <0.001 | No evidence of disease |
Unknown | 1.52 | 0.99–2.34 | 0.056 |