Skip to main content
. Author manuscript; available in PMC: 2018 Apr 27.
Published in final edited form as: JAMA Intern Med. 2013 May 13;173(9):797–804. doi: 10.1001/jamainternmed.2013.189

Table 3. Standardized Mean Change in Cognitive Scores by Randomization Group.

Mental Activity Control Mental Activity Intervention


Cognitive Test* Exercise Control (n=32) Exercise Intervention (n=31) Exercise Control (n=31) Exercise Intervention (n=32) p-value
Composite score .16 (.05, .26) .08 (-.004, .17) .17 (.03, .31) .22 (.12, .33) .26

Verbal learning & memory (RAVLT)
 No. words learned .33 (.09, .58) .14 (-.14, .43) .13 (-.11, .37) -.04 (-.42, .33) .38
 No. words recalled .01 (-.32, .33) .02 (-.28, .32) -.10 (-.36, .16) -.07 (-.46, .32) .93
Verbal fluency
 No. words, letter -.05 (-.33, .24) .08 (-.21, .37) .24 (-.11, .58) .22 (-.15, .58) .57
 No. words, category .06 (-.26, .38) -.07 (-.41, .26) .22 (-.06, .50) .18 (-.24, .60) .59
Processing speed (DSST)
 No. correct .15 (-.02, .32) .19 (.04, .33) .27 (.03, .51) .08 (-.13, .30) .71
Executive function/mental flexibility**
 Trails A, seconds -.36 (-.58, -.15) -.12 (-.32, .07) -.03 (-.50, .44) -.36 (-.63, -.08) .24
 Trails B, seconds -.22 (.45, .002) -.18 (-.49, .13) .13 (-.21, .48) -.25 (-.51, .01) .31
Executive function/inhibition (EFT)**
 Congruent reaction time, milliseconds -.17 (-.51, .16) .01 (-.42, .43) -.17 (-.41, .06) -.33 (-.55, -.11) .51
 Incongruent reaction time, milliseconds -.12 (-.36, .12) -.07 (-.48, .33) -.15 (-.52, .22) -.33 (-.58, -.08) .60
Visuospatial function (UFOV)**
 Processing speed, milliseconds -.23 (-.66, .19) -.04 (-.43, .34) -.17 (-.61, .26) -.39 (-.77, -.02) .65
 Divided attention, milliseconds -.13 (-.48, .22) -.17 (-.39, .05) -.60 (-.99, -.22) -.62 (-.97, -.26) .05
 Selective attention, milliseconds -.18 (-.59, .22) -.14 (-.43, .16) -.34 (-.58, -.11) -.71 (-.96, -.46) .02
*

RAVLT, Rey Auditory Verbal Learning Test; DSST, Digit Symbol Substitution Test; EFT, Eriksen Flanker Test; UFOV, Useful Field of View. Significant differences between mental activity intervention and mental activity control groups for UFOV-divided attention and UFOV-selective attention. No other significant differences between mental activity intervention and mental activity control groups (ignoring exercise), exercise intervention and exercise control groups (ignoring mental activity), or all four randomization groups.

**

For timed tests, negative change reflects improvement (i.e., faster performance).