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. 2018 Apr 20;9:402. doi: 10.3389/fphar.2018.00402

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Copyright © 2018 Zheng, Qian, Chen, Ruan and Fan.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Rapamycin regulates expression of fibrotic genes after tendon injury. (A) Representative images of western blot analysis of LC3A/B, p62, Atg5, Atg7, and Beclin 1 after different treatments. (B) Densitometry of LC3A/B and p62 expression. (C) Representative images of western blot analysis of fibrotic gene expressions after different treatments. (D) Representative images of immunohistochemical staining and quantitative analysis for p-mTOR after different treatments. Scale bar: 50 μm. n = 5 in each group. The data are shown as the means ± SD. ^∗P < 0.05 and ^∗∗P < 0.01 compared with the control group.