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. 2018 Apr 27;37:90. doi: 10.1186/s13046-018-0762-y

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — HSP27 and DHT affected the tumor formation and metastasis in vivo using MDA-MB-453 cells. The effect of DHT and HSP27 knock-down on xenograft tumors growth and formation was described by tumor volume curve (a). Images of tumors removed from the mice (b). HE staining, immunohistochemistry staining for HSP27 and Ki67, and TUNEL staining were carried out on xenograft tumors (c). Representative images of liver with cancer cells invasion (d)