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. 2018 Apr 20;9:363. doi: 10.3389/fphar.2018.00363

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Copyright © 2018 Lazzerini, Bertolozzi, Finizola, Acampa, Natale, Vanni, Fulceri, Gamberucci, Rossi, Giabbani, Caselli, Lamberti, Cevenini, Laghi-Pasini and Capecchi.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Serum levels of calcium, potassium and sodium in TdP patients taking or not taking PPIs. (A) Serum calcium levels. Patients taking PPIs (PPI+), n = 20; patients not taking PPIs (PPI−), n = 17. Two-tail Student's unpaired t-test (p > 0.05). Horizontal dotted line indicates the lower limit of reference values for calcium levels, i.e., 8.0 mg/dl. (B) Serum potassium levels. PPI+, n = 27; PPI−, n = 18. Two-tail Student's unpaired t-test (p > 0.05). Horizontal dotted line indicates the lower limit of reference values for potassium levels, i.e., 3.5 mEq/L. (C) Serum sodium levels. PPI+, n = 28; PPI−, n = 20. Two-tail Student's unpaired t-test (p > 0.05). Horizontal dotted line indicates the lower limit of reference values for sodium levels, i.e., 132 mEq/L.