Table 2.
Control | Bleomycin-treated | Significance | ||||
---|---|---|---|---|---|---|
Vehicle | ACE2 | Vehicle | ACE2 | Bleo: | ACE2: | |
White blood count (109/L) | 1.7 | 2.2 | 2.6 | 2.5 | 0.037 | |
Neutrophil # (109/L) | 0.6 | 0.9 | 1.2 | 1.2 | 0.009 | |
Lymphocyte # (109/L) | 1.1 | 1.2 | 1.3 | 1.2 | ||
Monocyte # (109/L) | 0.08 | 0.10 | 0.10 | 0.12 | ||
Hematocrit (%) | 49.3 | 52.2 | 51.8 | 54.1 | ||
Red cell distribution width (%) | 13.8 | 13.9 | 14.2 | 14.3 | 0.015 | |
Platelet count (109/L) | 837.1 | 717.7 | 1005.6 | 941.9 | 0.013 | |
Mean platelet volume (fL) | 5.23 | 5.37 | 5.33 | 5.39 | 0.027 |
Data are mean ± SEM, n = 7, 7, 14, and 15 for the control, ACE2, Bleo and Bleo+ACE2 groups respectively; comparisons between groups were made with two-way ANOVA followed by Holm-Sidak's multiple comparison post-test.