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. 2018 Apr 10;9(27):18786–18796. doi: 10.18632/oncotarget.24666

Table 2. Patient and tumor characteristics in: HPV single vs. multiple, HPV alpha 7 or 9 vs. alpha7+9 containing tumors.

Single infections Multiple infections Statistics
Mean age (years) 58.9 63.4 t-test; p=0.204
Mean tumor size (mm) 41.6 43.3 t-test; p=0.594
Type of histology
SCC 144/163 (88%) 22/25 (88%) Chi-square test; p=0.960
AC 19/163 (12%) 3/25 (12%)
Total 163 25
Tumor Stage
Early stage (FIGO I-II) 138/163 (85%) 19/25 (76%) Chi-square test; p=0.277
Advanced stage (FIGO III-IV) 25/163 (15%) 6/25 (24%)
Total 163 25
HPV Alpha 7/9 HPV Alpha 7+9 Statistics
Mean age (years) 59.0 64.3 t-test; p=0.333
Mean tumor size (mm) 41.8 46.8 t-test; p=0.267
Type of histology
SCC 147/166 (89%) 7/10 (70%) Chi-square test; p=0.085
AC 19/166 (11%) 3/10 (30%)
Total 166 10
Tumor Stage
Early stage (FIGO I-II) 137/166 (83%) 8/10 (80%) Chi-square test; p=0.838
Advanced stage (FIGO III-IV) 29/166 (18%) 2/10 (20%)
Total 166 10

The cervical HPV-positive single strain (n=163) and HPV-positive multiple strain (n=25) groups and the HPV alpha 7 or 9 (n=163) and alpha 7+9 (n=10) groups did not show any statistical significant differences in patient mean age at diagnosis, type of histology, tumor size or tumor stage. SCC- Squamous cell carcinoma, AC-Adenocarcinoma.