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. 2018 Apr 10;9(27):18916–18928. doi: 10.18632/oncotarget.24828

Table 1. Demographic and clinical characteristics of patients (n = 144) with CIN and ICC treated at the Instituto Nacional de Cancerología-México from 2004 to 2017.

Variable CIN (n = 49) ICC (n = 95) P-value
n (%) n (%)
Age
 <30 15 (30.61%) 2 (2.11%) <0.001
 ≥30 34 (69.39%) 93 (97.89%)
Smoking statusa
 Smokers 5 (10.20%) 11 (11.57%) 1.00
 Non-smokers 44 (89.80%) 84 (88.43%)
Alcohol consumptionb
 Positive 0 (0.00%) 4 (4.21%) 0.36
 Negative 49 (100%) 91 (95.79%)
Body mass index, kg/m2
 Normal (18.5–24.9) 4 (15.38%) 31 (39.24%) 0.01
 Overweigth (25–29.9) 7 (26.92%) 27 (34.18%)
 Obesity (≥30) 15 (57.70%) 21 (26.58%)
 Unknownc 23 16
Hormone contraception usage
 Yes 17 (58.62) 13 (32.50%)
 No 12 (41.38) 27 (67.50%) 0.05
 Unknownc 20 55
Number of previous sexual partners
 1 16 (38.10%) 22 (64.71%) 0.61
 ≥2 26 (61.90%) 12 (35.29%)
 Unknownc 7 61
Human Papillomavirus (HPV)
 16 12 (63.15%) 48 (51.06%)
 18 3 (15.80%) 14 (14.90%) 0.49
 Othersd 4 (21.05%) 32 (34.04%)
 Unknownc 30 1 e

CIN: Cervical intraepithelial neoplasia. ICC: Invasive cervical cancer aSmoking was defined as any tobacco consumption during their lifetime. bAlcohol consumption was defined as any alcohol intake per week. cData not reported in the clinical files, and thus, this category was not included in the comparisons dOther HPVs include types 6, 11, 31, 43, 42, 45 and 58. Bold: statistically significant.