Table 1. Most significant miRNAs expressed in the saliva of CLP.
Saliva | |||||||
---|---|---|---|---|---|---|---|
Target | LipCleft | Normal | ΔΔCT | 2–(ΔΔCT) | Log2 (2–(ΔΔCT)) | ||
Mean CT | Mean ΔCT | Mean CT | Mean ΔCT | Lipcleft | Lipcleft | Lipcleft | |
hsa-let-7e | 28,03 | 5,24 | 27,77 | 3,41 | 1,83 | 0,28 | –1,83 |
hsa-miR-16 | 20,21 | –2,58 | 23,37 | –0,99 | –1,59 | 3,01 | 1,59 |
hsa-miR-24 | 18,83 | –3,96 | 22,15 | –2,21 | –1,75 | 3,36 | 1,75 |
hsa-miR-28-3p | 24,35 | 1,56 | 28,44 | 4,07 | –2,51 | 5,70 | 2,51 |
hsa-miR-127 | 31,82 | 9,03 | 31,25 | 6,89 | 2,15 | 0,23 | –2,15 |
hsa-miR-128a | 28,35 | 5,56 | 31,70 | 7,34 | –1,78 | 3,42 | 1,78 |
hsa-miR-132 | 24,15 | 1,36 | 27,82 | 3,45 | –2,09 | 4,27 | 2,09 |
hsa-miR-135b | 29,82 | 7,03 | 29,22 | 4,86 | 2,18 | 0,22 | –2,18 |
hsa-miR-141 | 31,94 | 9,15 | 30,06 | 5,69 | 3,45 | 0,09 | –3,45 |
hsa-miR-150 | 23,31 | 0,52 | 27,13 | 2,77 | –2,25 | 4,76 | 2,25 |
hsa-miR-186 | 22,89 | 0,10 | 26,07 | 1,70 | –1,60 | 3,03 | 1,60 |
hsa-miR-193a-5p | 24,56 | 1,77 | 28,14 | 3,77 | –2,01 | 4,02 | 2,01 |
hsa-miR-197 | 22,39 | –0,40 | 26,14 | 1,78 | –2,18 | 4,52 | 2,18 |
hsa-miR-223 | 13,55 | –9,24 | 16,76 | –7,61 | –1,63 | 3,10 | 1,63 |
hsa-miR-324-3p | 27,78 | 4,99 | 32,48 | 8,11 | –3,12 | 8,70 | 3,12 |
hsa-miR-328 | 24,10 | 1,31 | 27,85 | 3,48 | –2,17 | 4,50 | 2,17 |
hsa-miR-342-3p | 23,54 | 0,75 | 27,18 | 2,81 | –2,06 | 4,18 | 2,06 |
hsa-miR-345 | 23,79 | 1,00 | 27,63 | 3,26 | –2,27 | 4,81 | 2,27 |
hsa-miR-361 | 27,58 | 4,79 | 31,20 | 6,84 | –2,05 | 4,14 | 2,05 |
hsa-miR-484 | 19,77 | –3,03 | 23,78 | –0,58 | –2,44 | 5,43 | 2,44 |
mmu-miR-491 | 26,57 | 3,77 | 29,90 | 5,53 | –1,76 | 3,38 | 1,76 |
hsa-miR-502-3p | 31,31 | 8,52 | 35,01 | 10,65 | –2,12 | 4,36 | 2,12 |
hsa-miR-517c | 35,43 | 12,64 | 34,67 | 10,31 | 2,33 | 0,20 | –2,33 |
hsa-miR-532 | 25,22 | 2,43 | 28,53 | 4,16 | –1,74 | 3,33 | 1,74 |
hsa-miR-652 | 26,44 | 3,65 | 30,26 | 5,90 | –2,24 | 4,73 | 2,24 |
hsa-miR-660 | 25,01 | 2,21 | 28,21 | 3,85 | –1,63 | 3,10 | 1,63 |
hsa-miR-744 | 26,91 | 4,12 | 30,29 | 5,92 | –1,80 | 3,47 | 1,80 |
hsa-miR-212 | 29,15 | 6,36 | 33,43 | 9,07 | –2,71 | 6,52 | 2,71 |
hsa-miR-511 | 32,48 | 9,68 | 31,88 | 7,52 | 2,17 | 0,22 | –2,17 |
Differentially expressed miRNAs between patients affected by lip and palatal cleft and healthy individuals.