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. 2018 Apr 10;9(27):19006–19013. doi: 10.18632/oncotarget.24873

Figure 2. Circulating exosomal Glypican-1 (GPC1) is a marker of PDAC disease burden.

Figure 2

(A) In matched samples, Glypican-1 (GPC1) is enriched in circulating exosomes (crExos; n = 11) compared to their source PDAC tissues (n = 11; ***P < 0.001). (B) The crExos GPC1 levels were found to decrease post-operatively after surgical resection when compared to matched pre-operative samples from the same patients (n = 11 vs. 11; *P < 0.05). (C) PDAC tissues with high GPC1 expression did not have crExos with higher GPC1 levels in matched samples.