Table 6. Odds ratios (ORs) and 95% confidence intervals (95% CIs) for breast cancer associated with AMH concentration by menopausal status at diagnosis.

	AMH quartiles1				Ptrend4	Pinteraction5
	Q1	Q2	Q3	Q4
Matched sets with both case and control(s) pre-menopausal at diagnosis/index date						0.34
Cases/Controls	222/292	282/339	327/369	369/374
Adjusted OR2 (95% CI)	1.00 (Referent)	1.21 (0.93, 1.56)	1.17 (0.91, 1.50)	1.35 (1.05, 1.73)	0.03
Matched sets with both case and control(s) post-menopausal at diagnosis/index date
Cases/Controls	161/176	90/116	96/94	100/75
Adjusted OR2 (95% CI)	1.00 (Referent)	0.88 (0.60, 1.30)	1.14 (0.74, 1.76)	1.61 (1.03, 2.53)	0.03
Adjusted OR3 (95% CI)	1.00 (Referent)	0.88 (0.59, 1.30)	1.13 (0.72, 1.79)	1.59 (0.96, 2.63)	0.06

¹Defined using cohort- and age-specific cutpoints.

²Estimated using conditional logistic regression model, adjusting for race/ethnicity (white, black, other or unknown), education (high school or less, some college or higher, unknown), BMI (<18.5, 18.5-25, 25-30, 30+ kg/m²), age at menarche (ordered categorical, <12, 12, 13, 14+ years), parity (ordered categorical, 0, 1, 2, 3+), age at 1^st FTP (ordered categorical, <=20, 21-25, 26-30, 30+ years or nulliparous), oral contraceptive use (never, former, current, unknown), partial oophorectomy (no, yes, unknown), family history of breast cancer (no, yes), benign breast biopsy (no, yes, unknown), and smoking status (never, former, current, unknown). Analyses were performed among women with known age at menopause.

³Estimated using conditional logistic regression model and adjusting for variables in footnote 2 and age at menopause.

⁴P_trend was calculated using ordered categorical AMH.

⁵P_interaction was calculated by including an interaction term between AMH (ordered categorical) and menopausal status at diagnosis.