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. 2018 Apr 21;5(1):e000277. doi: 10.1136/bmjresp-2018-000277

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© Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

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Change in FEV₁/FVC (z-scores) over time. All values on y-axis are presented as z-scores from FEV₁/FVC for Classic (A) and Later-Onset (B) patients, respectively, whereas age (in years) is represented by x-axis. Median (IQR) spirometric follow-up time was 7.7 (3.7–10.1) years.