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. 2018 Apr 27;4(4):eaao1170. doi: 10.1126/sciadv.aao1170

Fig. 3. Polydispersity in adhering cells for ΔFF.

Fig. 3

(A) Number of wobbling and pivoting cells on the lower surface before capillary inversion and (B and C) on the upper and lower surface after capillary inversion. Solid lines in panels A to C are from simulations with a minimal kinetic model. Data correspond to the inversion experiments in Fig. 2 (C and F). (D) Histogram showing the fraction of time cells are identified as wobbling on the lower surface before inversion, as in experiments (from a total of 117 movies over six different positions recorded between 4 and 12 hours before capillary inversion) and simulations. (E) Probabilities for a cell in a wobbling (W) or pivoting (P) state at time t to be found wobbling, pivoting, or off the surface (O) at a later time t + Δt (lines are for the kinetic model). (F) Schematic of weakly and strongly adhering cells: filled red circle, bound adhesive patch; empty circles, unbound adhesive patch.