Figure 6. Electrical properties of FUS^WT and FUS^P525L motoneurons innervating ankle flexor muscles at P180.

(A) Comparison of the resting membrane potential of FUS^WT (blue box, circles) vs. FUS^P525L (red box, diamonds) motoneurons innervating ankle flexor muscles at P180, split according to whether they were able (filled symbols) to fire repetitively or not (empty symbols, hatched box-and-whisker plot). (B) Comparison of the current required to elicit the first spike on a ramp of current (recruitment current) of FUS^WT (blue box, circles) vs. FUS^P525L (red box, diamonds) motoneurons. (C) Relationship between recruitment current and input conductance of FUS^WT (blue circles) vs. FUS^P525L (red diamonds) motoneurons. In all panels, the definition of the box-and-whisker plots is the same as in Figure 3.