. 2018 Apr 5;7:e33549. doi: 10.7554/eLife.33549

Table 1. Reaction rates and stoichiometry of the two-ODE model.

Reaction	Rate	Stoichiometry
Active Cdk1 Synthesis	$ρ_{1} = k_{s y}$	$< C d k 1_{a} >=< C d k 1_{a} > + 1$
Active Cdk1 to Inactive Cdk1	$ρ_{2} = \sqrt{r} (a_{W e e 1} + \frac{b_{W e e 1} E C 50_{W e e 1}^{n_{W e e 1}}}{< C d k 1_{a} >^{n_{W e e 1}} + E C 50_{W e e 1}^{n_{W e e 1}}}) < C d k 1_{a} >$	$< C d k 1_{a} >=< C d k 1_{a} > - 1$ $< C d k 1_{i} >=< C d k 1_{i} > + 1$
Inactive Cdk1 to Active Cdk1	$ρ_{3} = \frac{1}{\sqrt{r}} (a_{C d c 25} + \frac{b_{C d c 25} < C d k 1_{a} >^{n_{C d c 25}}}{< C d k 1_{a} >^{n_{C d c 25}} + E C 50_{C d c 25}^{n_{C d c 25}}}) < C d k 1_{i} >$	$< C d k 1_{a} >=< C d k 1_{a} > + 1$ $< C d k 1_{i} >=< C d k 1_{i} > - 1$
Active Cdk1 Degradation	$ρ_{4} = (a_{d e g} + \frac{b_{d e g} < C d k 1_{a} >^{n_{d e g}}}{< C d k 1_{a} >^{n_{d e g}} + E C 50_{d e g}^{n_{d e g}}}) < C d k 1_{a} >$	$< C d k 1_{a} >=< C d k 1_{a} > - 1$
Inactive Cdk1 Degradation	$ρ_{5} = (a_{d e g} + \frac{b_{d e g} < C d k 1_{a} >^{n_{d e g}}}{< C d k 1_{a} >^{n_{d e g}} + E C 50_{d e g}^{n_{d e g}}}) < C d k 1_{i} >$	$< C d k 1_{i} >=< C d k 1_{i} > - 1$