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. 2018 Apr 5;7:e33549. doi: 10.7554/eLife.33549

Table 2. Reaction rates in the model considering ATP.

Reaction Rate
Active Cdk1 Synthesis

ρ1=ksy

Active Cdk1 to Inactive Cdk1

ρ2=2[ATP]<Cdk1a>(aWee1+bWee1EC50Wee1nWee1<Cdk1a>nWee1+EC50Wee1nWee1)1-ATPATP1-2Wee10Wee1tot+Wee10Wee1tot

Inactive Cdk1 to Active Cdk1

ρ3=<Cdk1i>(aCdc25+bCdc25<Cdk1a>nCdc25<Cdk1a>nCdc25+EC50Cdc25nCdc25)ATP1-Cdc25-Pi0Cdc25tot+(2Cdc25-Pi0Cdc25tot-1)[ATP]

Active Cdk1 Degradation

ρ4=(adeg+bdeg<Cdk1a>ndeg<Cdk1a>ndeg+EC50degndeg)<Cdk1a>

Inactive Cdk1 Degradation

ρ5=(adeg+bdeg<Cdk1a>ndeg<Cdk1a>ndeg+EC50degndeg)<Cdk1i>