FIG 6.

WNV-I CD8⁺ T cells are tissue-resident T cells in the CNS. WNV-I CD8⁺ T cells (5 × 10⁴) were transferred into congenically marked mice. Three days later, the recipients were infected with 100 PFU of WNV-TX s.c., and on the day of sacrifice, the mice received 10 μg of allophycocyanin-labeled anti-CD8 antibody for 5 min through the i.v. route. (A and B) MFI (A) and representative histograms (B) on day 7 p.i. The data are representative of the results of two independent experiments with at least 5 mice per condition. *, P < 0.05; paired t test.