TABLE 5.
Compound | Papp(A-B) (10−6, cm/s) | Papp(B-A) (10−6, cm/s) | Efflux ratio | Recovery (%) |
|
---|---|---|---|---|---|
AP→BL | BL→AP | ||||
Propranolol | 34.38 | 19.50 | 0.57 | 90.69 | 95.53 |
Digoxin | 0.61 | 20.25 | 33.17 | 82.73 | 95.58 |
BHBM | 14.28 | 4.71 | 0.33 | 41.88 | 39.05 |
D13 | 0.13 | 0.22 | 1.74 | 49.82 | 106.98 |
Papp(A-B), permeability value apical to basolateral; Papp(B-A), permeability value basolateral to apical.