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. 2018 Apr 26;62(5):e00156-18. doi: 10.1128/AAC.00156-18

TABLE 5.

Caco-2 permeability of BHBM and D13a

Compound Papp(A-B) (10−6, cm/s) Papp(B-A) (10−6, cm/s) Efflux ratio Recovery (%)
AP→BL BL→AP
Propranolol 34.38 19.50 0.57 90.69 95.53
Digoxin 0.61 20.25 33.17 82.73 95.58
BHBM 14.28 4.71 0.33 41.88 39.05
D13 0.13 0.22 1.74 49.82 106.98
a

Papp(A-B), permeability value apical to basolateral; Papp(B-A), permeability value basolateral to apical.